Kerman University of Medical Sciences
1. Blood Lead Levels in Opium-Poisoned Children: One Cross-Sectional Study in Iran

Arezoo Chouhdari; Fariba Farnaghi; Hossein Hassanian‐Moghaddam; Nasim Zamani; Shahram Sabeti; Hadi Shahrabi Farahani

Volume 12, Issue 3 , Summer 2020, , Pages 159-166

Abstract
  Background: Lead poisoning is now more common due to accidental or intentional exposure to opiumimpregnated with lead. We aimed to determine the relationship between the blood lead levels (BLLs) andbasic characteristics in opium-poisoned children.Methods: In this cross-sectional study, 32 children younger ...  Read More

2. Consequences of Opioid Abuse and their Treatments in Persian Medicine: A Review Study

Mohadese Kamali; Haleh Tajadini; Mehrzad Mehrabani; Masoud Moghadari

Volume 12, Issue 1 , Winter 2020, , Pages 46-57

Abstract
  Background: Drug addiction is a major health problem for modern human communities. The earliest historicalevidence of opium use can be found in the writings of Theophrastus in the 3rd century BC. Since then, opiumuse and abuse has spread to all corners of the world, specifically the Eastern countries. ...  Read More

3. Lead Contamination of Opium, Opium Tincture, and Methadone Oral Solution, in Iran

Mitra Rahimi; Mohammad Amin Eshraghi; Shahin Shadnia

Volume 12, Issue 1 , Winter 2020, , Pages 34-39

Abstract
  Background: The present study is conducted with the aim to assess the lead contamination in opium tincture,methadone oral solution, and opium.Methods: 10 samples from each of the matters of opium tinctures, methadone oral solutions, and opium(provided by the Law Enforcement Force of the Islamic Republic ...  Read More

4. Cerebrospinal Fluid and Spinal Anesthesia Parameters in Healthy Versus Opium-Addict Patients during Lower Limb Surgery

Pooya Derakhshan; Farnad Imani; Seyed Alireza Seyed-Siamdoust; Sorour Garousi; Nasrin Nouri

Volume 12, Issue 1 , Winter 2020, , Pages 11-17

Abstract
  Background: Studies have reported lower pain threshold, spinal anesthesia duration, and level of sensoryblock in addicts compared to non-addict patients undergoing spinal anesthesia for surgery. Moreover, bloodgas and cerebrospinal fluid (CSF) were likely to be affected as well. The aim in the present ...  Read More

5. Blood Lead Level in Opiate Addicts Hospitalized in the Intensive Care Unit of a Trauma Referral Center in Kerman, Iran

Mehdi Ahmadinejad; Maryam Ahmadipour; Kouros Divsalar

Volume 11, Issue 1 , Spring 2019, , Pages 11-17

Abstract
  Background: Opium is the most commonly-used narcotic in Iran and some Asian countries. There are many reports of lead poisoning in opium users. Lead poisoning encompasses a wide range of symptoms the incidence and severity of which depend on the concentration and duration of contact with lead. The present ...  Read More

8. Comparison of Sexual Function and Serum Testosterone Levels in Men Opiate Addicts, under Methadone Maintenance Therapy, and Healthy Men

Parvin Agha-Mohammadhasani; Mohammadreza Mokhtaree; Alireza Nazari; Amir Rahnama

Volume 10, Issue 2 , Spring 2018, , Pages 76-85

Abstract
  Background: Substance abuse and consequently the use of methadone in Iran are reported at high levels. Drugs alter sexual function by affecting the organs of the body. The aim of this study was to evaluate sexual functioning and serum testosterone levels in opiate addicts, individuals receiving methadone ...  Read More

9. Immunohistochemical Evaluation of P53 and Epidermal Growth Factor Receptor Proteins Expression Levels in Gingival Tissue of Opium-dependent Patients

Mohammad Mohammadi; Najmeh Asghari; Mahtab Hashemipoor; Shima Borji; Molouk Torabi

Volume 9, Issue 4 , Autumn 2017, , Pages 222-228

Abstract
  Background: Although evidence indicates that tobacco use is one of the risk factors for oral cancer, the relationship between opium addiction and oral cancer has not yet been evaluated. The present study was performed aiming to evaluate P53 and epidermal growth factor receptor (EGFR) expression in the ...  Read More

10. An Investigation of the Risk Factors of Osteoporosis and the Correlation between Opium Consumption and Osteoporosis in Adults

Zeinab Heidari; Armita Shahesmaeili; Mohammad Reza Khajeh-Bahrami; Mandana Rezazadeh-Mehrizi; Mohammad Hossein Gozashti; Vahid Moazed

Volume 9, Issue 4 , Autumn 2017, , Pages 214-221

Abstract
  Background: Osteoporosis and osteopenia are the most common metabolic bone diseases making the patients vulnerable to bone fragility and fracture. In this study, the association of opium consumption and osteoporosis adjusted for other risk factors was studied.Methods: In this cross-sectional study, 619 ...  Read More

11. Risk Factors of Mortality Due to Acute Opium Poisoning: A Report from the Largest Intoxication Referral Center in Iran

Sahar Rismantab-Sani; Babak Soltani; Siamak Soltani; Azadeh Memarian

Volume 9, Issue 2 , Summer 2017, , Pages 96-102

Abstract
  Background: Studies have shown that Iran has a high rate of opiate abuse and the most prevalently used is opium. This study was aimed to evaluate risk factors in patients with acute opium intoxication who referred to Loghman Hakim Hospital, Tehran, Iran, in 2011.Methods: A total number of 383 patients ...  Read More

12. A Case-Control Study of Comparison of Plasma Levels of Matrix Metalloproteinase-9 in Inhaled Opium Addicts and Clinically Healthy Persons

Maryam Amizadeh; Shahryar Dabiri; Armin Javedan; Ali Eftekharian; Aliasghar Arabi

Volume 9, Issue 1 , Spring 2017, , Pages 11-16

Abstract
  cancer invasion and lymphatic metastasis. Smoking has been reported to increase the metalloproteinase level, but the role of opium consumption in metalloproteinase level has not yet been examined. The current research intended to examine the impacts of opium consumption on the serum levels of metalloproteinase.Methods: ...  Read More

13. Comparing Blood Lead Level among Oral/inhaled Opium Addicts with a Non-addict Control Group in the Southeast of Iran

Alireza Nemati; Shima Jafari; Mahdi Afshari; Somayeh Dahmardeh; Kaveh Tabrizian

Volume 8, Issue 4 , Autumn 2016, , Pages 235-241

Abstract
  Background: Opium is widely used among addicts in the Middle East countries such as Iran. Recent reports suggest that opium sellers cheat their customers by adding lead to the opium. Contaminated opium can threaten the health of consumers. This study was designed to evaluate the lead concentration in ...  Read More

14. Investigating Changes in Serum Biochemical Parameters in Opium Addicts Before and During Addiction Treatment

Sedigheh Barzehkar; Mohammad Hossein Gozashti; Kouros Divsalar; Mahdieh Mashrouteh; Amir Hossein Darvishi-Lardi

Volume 8, Issue 4 , Autumn 2016, , Pages 211-217

Abstract
  Background: Iran is one of the major consumers of opium and opiate substances in the world. Addiction has become a very important issue in the 21st century and an urgent one in Iran. The consumption of this substance leaves a variety of impacts on the human body. The goal of this study is to investigate ...  Read More

15. An Ecological Study of the Association between Opiate Use and Incidence of Cancers

Hamideh Rashidian; Kazem Zendehdel; Farin Kamangar; Reza Malekzadeh; Ali Akbar Haghdoost

Volume 8, Issue 4 , Autumn 2016, , Pages 252-260

Abstract
  Background: Cancer is the second leading cause of death after cardiovascular disease. In recent years it has been hypothesized that opiate use could be a risk factor for cancer. This study aimed to evaluate a possible association between opiate use and common cancers using ecological statistics from ...  Read More

16. The Effects of Opium Addiction on the Immune System Function in Patients with Fungal Infection

Seyyed Amin Ayatollahi-Mousavi; Gholamreza Asadikaram; Nouzar Nakhaee; Alireza Izadi; Nasser Keikha

Volume 8, Issue 4 , Autumn 2016, , Pages 218-226

Abstract
  Background: The use of narcotics such as opium exposes addicts as susceptible targets of different diseases so that they might easily be exposed to different diseases such as fungal infections. The present study aimed to investigate the effects of addiction to opium and fungal infection on plasma levels ...  Read More

17. Effects of Opium Addiction and Cigarette Smoking on Hematological Parameters

Gholamabbas Shahabinejad; Majid Sirati-Sabet; Mohammad Kazemi-Arababadi; Saeideh Nabati; Gholamreza Asadikaram

Volume 8, Issue 3 , Autumn 2016, , Pages 179-185

Abstract
  Background: The aim of the present study was to investigate the effects of opium addiction and cigarette smoking on the complete blood count (CBC).Methods: Eighty-six male subjects, including 31 opium-addicted cigarette smokers (OACS), 19 opium-addicted non-cigarette smokers (OANCS), 17 non-opium-addicted ...  Read More

18. Marketed New Drug Delivery Systems for Opioid Agonists/Antagonists ‎Administration: A Rapid Overview

Hoda Soltani; Abbas Pardakhty

Volume 8, Issue 2 , Spring 2016, , Pages 115-122

Abstract
  Novel drug delivery systems for controlled-release of opioid agonists as a long time painkillers or opioid antagonists for opium, heroin, and alcohol addiction are under development or in clinical use today. In this article, the field of “new drug delivery systems” is momentarily reviewed from the ...  Read More

19. Comparison of Quantitative and Qualitative Dermatoglyphic Characteristics ‎of Opium Addicts with Healthy Individuals

Omid Mehrpour; Ardeshir Sheikhazadi; Afsoon Barzegar; Afzal Husein; Claudia Malic; Elham Sheikhazadi; Seyed Hossein Saberi-Anary

Volume 8, Issue 2 , Spring 2016, , Pages 76-83

Abstract
  Background: Recreational drugs have a significant impact on the lives of drug users, their close families and friends, as well as their society. Social, psychological, biological, and genetic factors could make a person more prone to using recreational drugs. Finger and A-B ridges (dermatoglyphics) are ...  Read More

20. Effects of Different Concentrations of Opium on the Secretion of ‎Interleukin-6, Interferon-γ and Transforming Growth Factor Beta Cytokines ‎from Jurkat Cells

Gholamreza Asadikaram; Somayeh Igder; Zahra Jamali; Nader Shahrokhi; Hamid Najafipour; Mostafa Shokoohi; Abdollah Jafarzadeh; Mohammad Kazemi-Arababadi

Volume 7, 1-2 , Winter 2015, , Pages 47-53

Abstract
  Background: The risk of infectious, autoimmune and immunodeficiency diseases and cancers rise in opioid addicts due to changes in innate and acquired immune responses. Three types of opioid receptors (К،δ،μ) are expressed on the surface of lymphocytes and mononuclear phagocytes. The present study ...  Read More

21. Changes in Serum Biochemical Factors Associated with Opium Addiction ‎after Addiction Desertion

Mohammad Reza Afarinesh; Tahereh Haghpanah ‎; Kouros Divsalar ‎; Elham Dehyadegary ‎; Azar Shaikh-Aleslami ‎; Majid Mahmoodi ‎

Volume 6, 3-4 , Summer 2014, , Pages 138-145

Abstract
  Introduction: The long time use of opium has some effects on serums biochemical factors, the determination of this variation is a new approach in understanding off addiction and relive of drug abuser health. Hence in this study, these indicators in person who were withdrawing of opium have been studied. ...  Read More

22. Potential Effect of Opium Consumption on Controlling Diabetes and Some Cardiovascular Risk Factors in Diabetic Patients

Najmeh Rahimi; Mohamad Hossain Gozashti; Hamid Najafipour; Mostafa Shokoohi; Hamid Marefati

Volume 6, 1-2 , Winter 2014, , Pages 1-6

Abstract
  Background: Due to this belief that opium may have beneficial effects on diabetes or cardiovascular risk factors, the present study aimed to assess the potential and possible effects of opium consumption on diabetes control and some cardiovascular risk factors in diabetic patients. Methods: This study ...  Read More