Investigating the Effect of Substance Desire and Child Abuse in Adolescent Suicide Attempt

Document Type : Original Article


1 Department of Clinical Toxicology, Isfahan Clinical Toxicology Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

2 Department of Clinical Toxicology, Isfahan Clinical Toxicology Research Center, Khorshid Hospital, Isfahan University of Medical Sciences, Isfahan, Iran

3 Department of Clinical Toxicology, School of Medicine, Isfahan Clinical Toxicology Research Center, Khorshid Hospital, Isfahan University of Medical Sciences, Isfahan, Iran

4 Department of Clinical Toxicology, School of Medicine, Isfahan Clinical Toxicology Research Center, Khorshid Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.

5 Department of Clinical Toxicology, Isfahan Clinical Toxicology Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran



Background: This study aimed to investigate the impact of child abuse and substance desire on adolescent suicide.
Methods: This cross-sectional analytical study was conducted on all adolescents aged 12 to 19 who attempted suicide in 2018 
at Khorshid Hospital, Isfahan, Iran. A checklist of the patients’ demographic information, toxicological data, and 2 standard 
questionnaires, including substance desire (family, personal, social) and child abuse questionnaire (emotional abuse, physical 
abuse, and neglect abuse), were collected. The data were analyzed using SPSS version 15. Comparisons between the 2 groups 
were performed using t tests, chi-square tests, regression analysis, and crude model analysis. Odds ratio (OR) and 95% confidence 
interval were calculated based on logistic regression.
Findings: A total of 196 teenagers were included in the study, with a mean age of 16.48±1.6 years. Out of these, 155 individuals 
(79.1%) were female, resulting in a female-to-male ratio of 3.78. There was a significant relationship between gender and alcohol 
consumption in the personal aspect, as well as between the history of psychiatric diseases and alcohol consumption in the physical 
aspect (P<0.005). The previous history of suicide was the only variable that showed significance in all aspects of both the substance 
desire and child abuse questionnaires. History of neglect abuse (OR: 1.2, 95% CI [1.07–1.41]; P=0.009) was a predictive factor for 
suicide attempt. However, being male (OR: 0.12, 95% CI [0.039–0.37], P=0.000), having no psychiatric history (OR: 0.23, 95% 
CI [0.10–0.52], P<0.001) and not consuming alcohol (OR 0.33, 95% CI 0.15–0.71, P=0.005) were identified as protective factors 
for attempted suicide.
Conclusion: A public health strategy for suicide prevention includes implementing prevention strategies aimed at reducing risk 
factors, such as alcohol consumption and the risk of neglect abuse


Farzad Gheshlagi: (Google Scholar) (PubMed)

Rokhsareh Meamar: (Google Scholar) (PubMed)

Fatemehalsadat Rastkerdar: (Google Scholar) (PubMed)

Azadeh Akbari Jebeli: (Google Scholar) (PubMed)

Ali Soleimanpour: (Google Scholar) (PubMed)

Shadi Haddad: (Google Scholar) (PubMed)

Nastaran Eizadi-Mood: (Google Scholar) (PubMed)


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