Determining the Short-term Effects of Smoking Cessation Using Nicotine Gum on Oral Health-Related Quality of Life: A Pilot Study

Document Type : Original Article


1 Department of Oral Medicine, Faculty of Dentistry, Kerman University of Medical Sciences, Kerman, Iran

2 General Dentist, Faculty of Dentistry, Kerman University of Medical Sciences, Kerman, Iran

3 Department of Community Dentistry, Faculty of Dentistry, Kerman University of Medical Sciences, Kerman, Iran



Background: Nowadays, the adverse effects of smoking on general, oral, and dental health are reported time and again 
worldwide. However, evidence to quantify the effects of tobacco smoking and smoking cessation on health-related quality of 
life (HRQoL) and oral health-related quality of life (OHQoL) is inadequate. Accordingly, this study aimed to assess the effects of 
nicotine gum on HRQoL and OHQoL of cigarette smokers.
Methods: This pilot study was conducted on 40 smokers, half of whom received nicotine gum. HRQoL and OHQoL were 
measured twice at the beginning of the study and after three months using standard versions of Short Form Health Survey (SF-12) 
and Oral Health Impact Profile (OHIP-5) questionnaires. T-test, Fischer’s exact test, and Pearson’s correlation coefficient were 
used to compare the participants’ scores on the questionnaires. 
Findings: The mean age of the participants was 43.39±12.32 years. Using nicotine gum significantly increased the scores of 
general health (P=0.046) and physical functioning (P=0.021) domains of HRQoL in comparison with the cigarette smoking 
group. Moreover, using nicotine gum significantly increased the scores of the two questions about the reduced sense of taste 
(P<0.001) and difficulty doing usual jobs (P=0.071). 
Conclusion: Using nicotine gum was associated with the improvement of HRQoL and OHQoL to some extent. To better 
understand the relationship between smoking cessation and improved OHQoL, it is necessary to conduct further studies in this 


Nader Navabi: (Google Scholar) (PubMed)

Maryam-al-sadat Hashemipour: (Google Scholar) (PubMed)

Rana Ramezani: (Google Scholar) (PubMed)

Saghar Karimiafshar: (Google Scholar) (PubMed)

Fatemeh Najminouri: (Google Scholar) (PubMed)


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