Family-Based Contributors in Relapse and Relapse Prevention Among Patients with Substance Use Disorder: An Exploration of Risk and Prognostic Factors

Document Type : Original Article


1 Department of Psychiatry, Faculty of Medicine, Mansoura University, Mansoura, Egypt

2 1 Department of Psychiatry, Faculty of Medicine, Mansoura University, Mansoura, Egypt 2 Department of Psychiatry and Behavioral Science, College of Medicine and Health Sciences, National University of Science and Technology, Sohar, Sultanate of Oman

3 Department of Psychiatry and Behavioral Science, College of Medicine and Health Sciences, National University of Science and Technology, Sohar, Sultanate of Oman



Background: Substance use disorder (SUD) remains a significant public health issue, with a high relapse rate even after 
detoxification treatment. Family dysfunction has been identified as a closely related factor contributing to relapse in individuals 
with SUD. The objective of this study was to investigate the mediating role of family climate in the relapse tendency among 
patients with SUD.
Methods: The study employed a case-control design using the survey method. A total of 103 patients from the addiction unit 
daycare at Mansoura University Hospital were divided into 2 groups: the relapsed group and the abstinent group. The Relapse 
Tendency Questionnaire, the Family Climate Scale, and a structured interview were administered to collect sociodemographic 
Findings: The results revealed significant differences between the study groups in terms of sociodemographic risk factors, 
including marital status (P≤0.001), employment (P=0.043), and economic status (P=0.028). Additionally, a significant 
difference was observed between the study groups in terms of the Family Climate Scale (P=0.038). Female participants reported 
that familial factors had a greater influence on their relapse compared to male participants (P=0.005).
Conclusion: A statistically significant difference was found in the family climate subscale scores between the relapsed patients 
and the abstinent patients with SUD, confirming the influential role of family climate in the relapse process of SUD.


Hassan Mohammed Sonbol: (Google Scholar) (PubMed)

Mostafa Abdel-monem Amr: (Google Scholar) (PubMed)

Miriam Archana Simon: (Google Scholar) (PubMed)


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