%0 Journal Article %T Assessment of Cognitive Functions in Methadone Maintenance Patients %J Addiction and Health %I Kerman University of Medical Sciences %Z 2008-4633 %A Mazhari, Shahrzad %A Keshvari, Zeinab %A Sabahi, Abdolreza %A Mottaghian, Shirin %D 2015 %\ 08/15/2015 %V 7 %N 3-4 %P 109-116 %! Assessment of Cognitive Functions in Methadone Maintenance Patients %K Methadone maintenance %K opiates %K Cognitive dysfunction %R %X Background: Methadone maintenance has received little scientific attention regarding neurocognitive effects. This study is aimed to assess the neuropsychological performance of methadone maintenance patients (MMP) compared to those healthy controls. Methods: Thirty-five MMP and 35 healthy controls, matched for age, gender, education and employment status, examined on a battery of tests aimed at assessing verbal fluency, executive functions, verbal memory, and working memory, using controlled oral word association test (COWAT), trial making test (TMT) Part A and B, Rey auditory verbal learning test (RAVLT), and backward digit span. Findings: MMP performed significantly poorly than controls in cognitive domains of verbal fluency, executive function, and verbal memory. MMP did not exhibit impairment in working memory, and TMT Part A compared to controls. Conclusion: These results suggest that methadone consumption induces significant cognitive impairment that could compromise drug-treatment outcomes in MMP. %U https://ahj.kmu.ac.ir/article_84650_c82e6a7c20e06637690b13f3a89d024a.pdf