%0 Journal Article %T Loperamide Dependence: A Case Report %J Addiction and Health %I Kerman University of Medical Sciences %Z 2008-4633 %A Zarghami, Mehran %A Rezapour, Maryam %D 2017 %\ 05/04/2017 %V 9 %N 1 %P 59-63 %! Loperamide Dependence: A Case Report %K Loperamide %K Addiction %K Cardiac arrhythmia %R %X Background: Loperamide is used as an antidiarrheal drug and is available over-the-counter. It cannot pass the blood-brain barrier and it does not have a considerable abuse potential. It can lead to dangerous cardiac arrhythmia.Case Report: Herein, we report a 35-year-old man with a 13-year history of abusing opioids who had undergone detoxification for four times during this period. He underwent detoxification for using 200 mg loperamide daily with anticholinergic agents, clonidine, non-steroidal analgesics, and diazepam. No evidence of arrhythmia was seen in the patient.Conclusion: Tolerating high doses of loperamide could be dangerous and increases the risk of fatal cardiac arrhythmias. %U https://ahj.kmu.ac.ir/article_84708_e8f9dee7edffbed101084ce0e655d48d.pdf