@article { author = {Zarghami, Mehran and Rezapour, Maryam}, title = {Loperamide Dependence: A Case Report}, journal = {Addiction and Health}, volume = {9}, number = {1}, pages = {59-63}, year = {2017}, publisher = {Kerman University of Medical Sciences}, issn = {2008-4633}, eissn = {2008-8469}, doi = {}, abstract = {Background: Loperamide is used as an antidiarrheal drug and is available over-the-counter. It cannot pass the blood-brain barrier and it does not have a considerable abuse potential. It can lead to dangerous cardiac arrhythmia.Case Report: Herein, we report a 35-year-old man with a 13-year history of abusing opioids who had undergone detoxification for four times during this period. He underwent detoxification for using 200 mg loperamide daily with anticholinergic agents, clonidine, non-steroidal analgesics, and diazepam. No evidence of arrhythmia was seen in the patient.Conclusion: Tolerating high doses of loperamide could be dangerous and increases the risk of fatal cardiac arrhythmias.}, keywords = {Loperamide,Addiction,Cardiac arrhythmia}, url = {https://ahj.kmu.ac.ir/article_84708.html}, eprint = {https://ahj.kmu.ac.ir/article_84708_e8f9dee7edffbed101084ce0e655d48d.pdf} }